Pressure Cooker BBQ Pulled Pork ADVERTISEMENT Instructions Mix garlic powder, kosher salt, and black pepper together. Rub this mixture over the pork. Place the seasoned pork in an electric pressure cooker or Instant Pot. Drizzle liquid smoke over the pork. Cook on high pressure for 75 minutes. After cooking, allow a 15-minute natural release. Then, switch the release valve to the venting position. Remove the lid once steam stops. Adjust cooking time for roasts larger than 5 pounds. Shred the pork in the pressure cooker, mixing with the juices. Serve as is or mix in 1 cup homemade barbecue sauce for extra flavor. Combine all sauce ingredients in a bowl. Stir until well mixed.